Chemical name:CA index name: beta-D-mannopyranose, 1,3,4,6-tetraacetate 2-(trifluoromethane-sulfonate)Synonyms:TATM; mannose triflate; 1,3,4,6…

Chemical name:CA index name: beta-D-mannopyranose, 1,3,4,6-tetraacetate 2-(trifluoromethane-sulfonate)Synonyms:TATM; mannose triflate; 1,3,4,6-tetra-O-acetyl-2-O-trifluoro-methanesulfonyl-beta-D-mannopyranoseCAS RN[92051-23-5]M. F.C15H19F3O12SMol. Wt.480.37Characteristics:Colourless or nearly colourless crystals, mp 119 - 122 汣; soluble in acetonitrile, DMSO, methanol, acetone, insoluble in aqueous mediaPresentation:Packaged in dark glass vials (DIN 2R) with teflon-faced chlorobutyl stoppers, centre tear-off crimp caps, argon flushed. (100.0012.5), (100.0015) and (100.0020)Packaged in dark glass screw cap vials, argon flushed. (100.0100) and (100.1000)Certificate:CoA; identity, purity, melting point, 1H and 19F NMR spectra, IR spectrumPurity:> 99 %Order Number:100.0012.5: 12.5 mg per vial100.0015: 15 mg per vial100.0020: 20 mg per vial100.0100: 100 mg per vial1000.1000: 1 g per vialLiterature:1. Hamacher K. et al. Efficient stereospecific synthesis of no-carrier-added 2-[18F]fluoro-2-deoxy-D-glucose using amino-polyether supported nucleophilic substitution. J. Nucl. Med. 1986, 27, 235-238.2. Padgett H. et al. Computer-controlled radiochemical synthesis: a chemistry process control unit for the automated production of radiochemicals. Appl. Radiat. Isot. 1989, 40, 433-445.3. Pavliak V. et al. A short synthesis of 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-(-D-glucopyranose and the corresponding (-glucosyl chloride from D-mannose. Carbohydr. Res. 1991, 210, 333-337.4. Chirakal R. Traces of fluorine containing impurities in the mannose triflate and their adverse effect on the radiochemical yield of 2-18FDG. XIIth ISRC; Uppsala, Sweden 1997, 214-216.

Manufacturing and development of chemicals for nuclear medicine production and development of PET and SPECT precursors manufacturing of reagents kits, particularly kits for FDG production new service: design, synthesis and production of peptides custom synthesis and manufacturing according to GMP new: ROVER - PET evaluation software 80 professionals ( 12 with PhD. ) new manufacturing site and facilities for the production under pharmaceutical conditions class 100 audited and accepted as cGMP API manufacturer by - German pharmaceutical authorities - FDA ( US Food and Drug Administration )